British airways owner IAG lost 0.9pc after Britain removed Portugal from its quarantine-free travel list and added seven more countries to its red list.
The blue-chip FTSE 100 index was falt with banks and life insurers adding 0.6pc and 0.1pc, respectively. HSBC Holdings and Prudential provided the biggest boost.
The domestically focused FTSE 250 index rose 0.1pc, with aero and defence stocks adding 1.7pc. Meggitt gained 3.1pc after UBS upgraded the stock to "neutral" from "sell".
The FTSE 100 index has gained 8.9% year-to-date on optimism that speedy vaccine rollouts and constant policy support from the government would drive a stronger recovery from a pandemic-led recession.
The blue-chip FTSE 100 index inched 0.02% lower as heavyweight oil majors BP and Royal Dutch Shell and banking stocks, fell and a stronger pound weighed on the index.