"We look forward to the opportunity to lay out in very clear terms to our Chinese counterparts some of the concerns that we have about the actions they're taking," said Blinken.
They will continue on to South Korea, and a policy review by the new administration of its approach to Pyongyang is also a key part of the diplomatic outreach.
U.S. Secretary of State Antony Blinken warned China on Tuesday against using “coercion and aggression” as he sought to use his first trip abroad to shore up Asian alliances in the face of growing assertiveness by Beijing.
China’s extensive territorial claims in the East and South China Seas have become a priority issue in an increasingly testy Sino-U.S. relationship and are an important security concern for Japan.
But ultimately no progress was made towards Washington's declared aim of denuclearising North Korea, which is under multiple international sanctions for its banned weapons programmes.
The visit, from March 15 to 18, to Tokyo and Seoul is the first overseas trip by top cabinet members of President Joe Biden's administration and follows last week's Quad alliance summit of the leaders of the US, Japan, Australia and India.
The Quad summit pledged to work to ensure a free and open Indo-Pacific, a major priority for Tokyo, and cooperate on maritime, cyber and economic security in the face of challenges from Beijing.
"(The accusation) is a completely unfounded and spurious verdict against the Ethiopian government," the ministry of foreign affairs said in a statement on Saturday.
Nothing during or after the end of the main law enforcement operation in Tigray can be identified or defined by any standards as a targeted, intentional ethnic cleansing against anyone in the region.
In a sign of Biden's strategy to rally allies as a bulwark to China, Blinken will first travel to Japan and South Korea with Defense Secretary Lloyd Austin, who separately will head onward to India.
Discussions are likely to focus on China's policies toward Hong Kong, its pressure on Taiwan, its treatment of Uighurs, and what Washington sees as economic coercion against Australia, she said.
Sino-US relations re-emerged as another key market focus as US Secretary of State Antony Blinken will meet with top Chinese officials on March 18 in Alaska, the White House said on Wednesday, the first high-level in-person contact between the two sparring countries under the Biden administration.
The US government said on Sunday that all options remain on the table for its remaining 2,500 troops in Afghanistan and that it had made no decisions about its military commitment after May 1.
Blinken noted Ethiopian commitments to full accountability, including international support for investigations into human rights abuses and to allowing unhindered humanitarian access.