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World

Contaminant in Moderna vaccines in Japan suspected to be metallic particles: NHK

  • Japan on Thursday suspended the use of 1.63 million doses shipped to 863 vaccination centres nationwide, more than a week after the domestic distributor, Takeda Pharmaceutical, received reports of contaminants in some vials
Published August 27, 2021

TOKYO: A contaminant found in a batch of Moderna Inc's COVID-19 vaccines delivered to Japan is believed to be a metallic particle, Japanese public broadcaster NHK reported, citing sources at the health ministry.

Japan on Thursday suspended the use of 1.63 million doses shipped to 863 vaccination centres nationwide, more than a week after the domestic distributor, Takeda Pharmaceutical, received reports of contaminants in some vials.

NHK, in a report published late on Thursday, cited ministry sources as saying the particle reacted to magnets and was therefore suspected to be a metal. Moderna has described it as "particulate matter" that did not pose a safety or efficacy issue.

A health ministry official said the composition of the contaminant has not been confirmed. In a statement, Takeda said it asked Moderna to investigate the issue and that it would work with the health ministry to replace the affected vaccine supply.

Moderna completes filing process for full approval of COVID-19 vaccine

News of the contaminant could provide a fresh setback for Japan's inoculation drive as it struggles to persuade many - particularly young people - to get vaccinated.

On Friday, eight more prefectures entered a state of emergency meaning about 80% of Japan's population is under coronavirus restrictions. The government reported nearly 25,000 new infections and severe cases at a record 2,000 for Thursday.

The ministry has said the suspension of the Moderna batches was a precaution but it prompted several Japanese companies to cancel worker vaccinations and the European drugs regulator to launch an investigation.

Airline ANA Holdings Inc said it had secured more Moderna supplies and would resume inoculations on Saturday after a two-day suspension of the shots.

Japan stops use of 1.63 million Moderna doses over contamination

Spanish pharma company Rovi, which bottles Moderna vaccines for markets other than the United States, said the contamination could be due to a manufacturing issue on a production line. A spokesperson said the company could not say anything more while it was investigating.

Moderna put the lot in question and two adjacent ones on hold.

Another health ministry official said it would take "some time" to confirm how many shots from the contaminated batch had been administered in Japan. Kyodo News reported that at least 176,000 shots have been used based on its own tally of figures reported by municipalities.

About 54% of Japan's population has received at least one dose, according to a Reuters tracker. Taro Kono, the minister in charge of the vaccination programme, said he did not expect the contamination issue to have an impact on the government's goal of fully inoculating the adult population by November.

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