ANL 34.00 Increased By ▲ 0.90 (2.72%)
ASC 14.90 Increased By ▲ 0.55 (3.83%)
ASL 25.10 Increased By ▲ 0.62 (2.53%)
AVN 92.20 Decreased By ▼ -0.30 (-0.32%)
BOP 9.14 Increased By ▲ 0.08 (0.88%)
BYCO 9.85 Increased By ▲ 0.15 (1.55%)
DGKC 134.70 Increased By ▲ 2.51 (1.9%)
EPCL 50.62 Increased By ▲ 0.52 (1.04%)
FCCL 24.63 Increased By ▲ 0.33 (1.36%)
FFBL 25.86 Increased By ▲ 1.46 (5.98%)
FFL 15.49 Increased By ▲ 0.47 (3.13%)
HASCOL 10.56 No Change ▼ 0.00 (0%)
HUBC 86.33 Increased By ▲ 1.23 (1.45%)
HUMNL 7.02 Increased By ▲ 0.27 (4%)
JSCL 25.65 Increased By ▲ 0.40 (1.58%)
KAPCO 41.55 Increased By ▲ 2.80 (7.23%)
KEL 4.02 Increased By ▲ 0.04 (1.01%)
LOTCHEM 14.45 Increased By ▲ 0.02 (0.14%)
MLCF 46.42 Increased By ▲ 0.54 (1.18%)
PAEL 37.25 Increased By ▲ 0.55 (1.5%)
PIBTL 11.70 Increased By ▲ 0.27 (2.36%)
POWER 10.25 Increased By ▲ 0.10 (0.99%)
PPL 90.90 Increased By ▲ 1.20 (1.34%)
PRL 26.86 Increased By ▲ 0.61 (2.32%)
PTC 8.71 Increased By ▲ 0.11 (1.28%)
SILK 1.35 No Change ▼ 0.00 (0%)
SNGP 42.71 Increased By ▲ 1.31 (3.16%)
TRG 146.10 Increased By ▲ 3.00 (2.1%)
UNITY 30.20 Increased By ▲ 0.41 (1.38%)
WTL 1.41 Decreased By ▼ -0.01 (-0.7%)
BR100 4,965 Increased By ▲ 76.98 (1.57%)
BR30 25,754 Increased By ▲ 477.72 (1.89%)
KSE100 45,837 Increased By ▲ 558.82 (1.23%)
KSE30 19,174 Increased By ▲ 275.54 (1.46%)
World

New China swine fever strains point to unlicensed vaccines

  • But it has issued at least three warnings against use of unauthorised African swine fever vaccines, cautioning that they could have severe side effects and that producers and users could be charged with a criminal offence.
22 Jan 2021

BEIJING: A new form of African swine fever identified in Chinese pig farms is most likely caused by illicit vaccines, industry insiders say, a fresh blow to the world's largest pork producer, still recovering from a devastating epidemic of the virus.

Two new strains of African swine fever have infected more than 1,000 sows on several farms owned by New Hope Liuhe , China's fourth-largest producer, as well as pigs being fattened for the firm by contract farmers, said Yan Zhichun, the company's chief science officer.

Though the strains, which are missing one or two key genes present in the wild African swine fever virus, don't kill pigs like the disease that ravaged China's farms in 2018 and 2019, they cause a chronic condition that reduces the number of healthy piglets born, Yan told Reuters. At New Hope, and many large producers, infected pigs are culled to prevent the spread, making the disease effectively fatal.

Although the known infections are limited now, if the strains spread widely, they could slash pork output in the world's top consumer and producer; two years ago, swine fever wiped out half of China's 400 million-head pig herd. Pork prices are still at record levels and China is under pressure to strengthen food security amid the COVID-19 pandemic.

"I don't know where they come from, but we find some mild field infections caused by some sort of gene-deleted viruses," Yan said.

Wayne Johnson, a Beijing-based veterinarian, said he diagnosed a chronic, or less-lethal, form of the disease in pigs last year.

The virus lacked certain genetic components, known as the MGF360 genes. New Hope has found strains of the virus missing both the MGF360 genes and the CD2v genes, Yan said.

Research has shown that deleting some MGF360 genes from African swine fever creates immunity. But the modified virus was not developed into a vaccine because it tended to later mutate back to a harmful state.

"You can sequence these things, these double deletions, and if it's exactly the same as described in the lab, it's too much of a coincidence, because you would never get that exact deletion," said Lucilla Steinaa, principal scientist at the International Livestock Research Institute (ILRI) in Nairobi.

There is no approved vaccine for African swine fever, which is not harmful to humans. But many Chinese farmers struggling to protect their pigs have resorted to unapproved products, industry insiders and experts said. They fear illicit vaccines have created accidental infections, which are now spreading.

The new strains could proliferate globally through contaminated meat, infecting pigs that are fed on kitchen waste. The virus is known to survive for months in some pork products.

China's Ministry of Agriculture and Rural Affairs did not respond to two requests for comment.

But it has issued at least three warnings against use of unauthorised African swine fever vaccines, cautioning that they could have severe side effects and that producers and users could be charged with a criminal offence.

In August, the ministry said it would test pigs for different strains of the virus as part of a nationwide investigation into illegal vaccine use.

Any strains with gene deletions could indicate a vaccine had been used, it said. No findings have been published so far on the issue, which is highly sensitive for Beijing. Reporting of the recent African swine fever outbreaks was extensively covered up.