The S&P 500 and the Dow opened lower as a pause in Johnson & Johnson's COVID-19 vaccine trials weighed, while the Nasdaq rose ahead of major events scheduled for Apple and Amazon.com.
The Dow Jones Industrial Average fell 72.57 points, or 0.25pc, at the open to 28,764.95.
The S&P 500 opened lower by 0.21 points, or 0.01pc, at 3,534.01, while the Nasdaq Composite gained 25.50 points, or 0.21pc, to 11,901.76 at the opening bell.
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