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INDIANAPOLIS: A former FedEx employee fatally shot eight people and wounded several others at the delivery company's facility in the US city of Indianapolis before killing himself, authorities said Friday after the latest mass shooting to jolt the country.

Four of the dead were followers of the South Asian Sikh religion, a Sikh organization confirmed, raising questions about whether the gunman's motivation was in any way racially or ethnically motivated.

The Thursday night slayings came a week after President Joe Biden branded US gun violence an "epidemic" and an "international embarrassment" as he waded into the tense debate over firearms control, a sensitive American political issue. After this latest tragedy he again ordered flags flown at half staff at the White House and other public buildings.

Police in Indiana's capital city identified the gunman as 19-year-old Brandon Hole.

"FedEx officials have confirmed that Mr Hole was a former employee at the facility, and he was last employed in 2020," deputy police chief Craig McCartt told reporters. Authorities searched multiple locations and seized evidence in their effort to learn more about the shooter and a possible motive.

The Sikh Coalition, which announced "that at least four of those killed" were members of the Indianapolis Sikh community, said it expected "authorities will conduct a full investigation - including the possibility of bias as a factor."

"While we don't yet know the motive of the shooter, he targeted a facility known to be heavily populated by Sikh employees," said the coalition's executive director Satjeet Kaur.

Komal Chohan, whose grandmother was killed, described being "heartbroken" over the loss, adding that "our families should not feel unsafe at work, at their place of worship, or anywhere. Enough is enough."

FBI special agent Paul Keenan said Hole was interviewed by the FBI in April 2020 and had a shotgun seized by authorities, the Indianapolis Star reported.

It was not immediately clear whether Hole had been fired or left his job voluntarily, or if he knew the victims.

"He got out of his car and pretty quickly started some random shooting outside the facility. There was no confrontation with anyone that was there. There was no disturbance. There was no argument," McCartt said.

The shooting "began in the parking lot and then he did go into the building... for a brief period of time before he took his own life."

McCartt said the gunman was armed with a rifle.

"This is a devastating day and words are hard to describe the emotion we feel," said FedEx chairman Frederick Smith in a letter to employees, adding that the company was working with law enforcement.

Four people with gunshot wounds were transported by ambulance, including one in critical condition, while five people suffered other injuries, police said.

One man who was working a twilight shift at the FedEx Ground station, which reportedly employs more than 4,000 people, told local broadcaster WISH he saw the gunman start shooting and heard more than 10 shots.