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The service said its rescue boats intercepted 115 migrants travelling in five small boats in the Strait of Gibraltar on Sunday, a day after it pulled 293 migrants from nine vessels.
The maritime service is tracking three other boats carrying "a significant number of migrants" in the Alboran Sea east of the Strait of Gibraltar, a maritime rescue service spokesman told AFP.
Spain is the third busiest gateway for migrants arriving in Europe, still far behind Italy but catching up fast with Greece.