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The benchmark BSE index closed down 0.67 percent at 35,149.12.
The broader NSE index ended 0.54 percent lower at 10,682.7, closing below 10,700 for the first time in nine sessions.
Index heavyweights Housing Development Finance Corp and Reliance Industries Ltd were among the top drags, closing down 2.01 percent and 1.27 percent respectively.