WASHINGTON: US health experts said Friday that cases of monkeypox that are being detected at the moment do not necessarily display the usual symptoms, making the disease more difficult to diagnose.

The Centers for Disease Control and Prevention (CDC) stressed that identifying cases was crucial to curbing the spread of the disease.

"We have seen presentations of monkeypox that are mild and sometimes only limited areas of the body, which differs from the classic presentation seen in endemic countries in Western Central Africa," said Rochelle Walensky, head of the CDC.

"This has prompted concern that some cases may go unrecognized or undiagnosed," she added, urging increased vigilance among members of the medical profession and the public in general.

More than 700 monkeypox cases globally, 21 in US: CDC

Current cases do not always present flu-like symptoms, such as fever, body aches and swollen glands that typically precede the appearance of the rash characteristic of the disease.

Additionally, while these rashes typically appear all over the body, many current cases are limited to certain areas.

"It's important to be aware that monkeypox cases may present similar to some sexually transmitted infections," such as herpes, "and could be mistaken for other diagnoses," Walensky said.

The United States has now recorded 45 cases, she added, twice as many as last week. No deaths have been reported.

As of June 9, around 1,300 cases had been identified worldwide, she said.

Transmission requires close and prolonged contact between two people.

The United States is counting in particular on the vaccination of contact cases to stem the epidemic.