Tuesday
Masters Security (MAW) v Petro Luanda (ANG) 0-5, Cape Town City (RSA) v Young Buffaloes (SWZ) 1-0, Hafia (GUI) v Energie (BEN) 0-1, Anse Reunion (SEY) v APR (RWA) 0-4, Port Louis (MRI) v Ngazi (COM) 1-1, Deportivo Niefang (GEQ) v New Stars (CMR) 1-2, La Mancha (CGO) v Tanda (CIV) 0-0, Belouizdad (ALG) v Onze Createurs (MLI) 1-1, Green Buffaloes (ZAM) v Al Masry (EGY) 0-4, Gendarmerie Nationale (DJI) v Simba (TAN) 0-4
Wednesday
Jwaneng Galaxy (BOT) v Costa do Sol (MOZ) 0-1, Fosa Juniors (MAD) v Leopards (KEN) 1-1, Maniema Union (COD) v Mangasport (GAB) 1-0, Etoile Filante (BUR) v Olympique Star (BDI) 0-0, Hawks (GAM) v Akwa Utd (NGR) 2-1, Sahel (NIG) v Al Ittihad (LBA) 0-1, CARA (CGO) v Asante Kotoko (GHA) 0-1, Mbour Petite-Cote (SEN) v Renaissance Berkane (MAR) 1-2, Nouadhibou (MTN) v Africa Sports (CIV) 1-1, Welayta Dicha (ETH) v Zimamoto (ZAN) 1-1
Djoliba (MLI), Ben Guerdane (TUN) walkovers, Elwa Utd (LBR), Al Hilal (SSD) withdrew
Byes: Al Ahly Shendy, Al Hilal Obied (both SUD), SuperSport Utd (RSA), Enyimba (NGR), USM Alger (ALG), Motema Pembe (COD), Nkana (ZAM), Club Africain (TUN), Raja Casablanca (MAR), Zamalek (EGY)