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About three minutes into trading, the Dow Jones Industrial Average was at 24,897.88, down 0.1 percent.
The broad-based S&P 500 dipped 0.2 percent to 2,690.35, while the tech-rich Nasdaq Composite Index shed 0.4 percent to 7,08696.
After more than a year of tranquility and a steady upward climb, the violent market swings in recent days has reestablished volatility as a force in US stocks.
The Dow on Tuesday finished up 2.3 percent after a swing of almost 1,200 points between its peak and nadir during the session, following Monday's session which saw the biggest point decline on record.