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"In no case will we allow another Jungle here," he said in a speech in the northern city, as his government puts pressure on Britain to contribute more to dealing with migrants seeking to cross the Channel.
"Everything is being done to prevent illegal crossings," Macron said, saying Calais must not be used as an "entry door" to Britain.
The government of Macron's Socialist predecessor Francois Hollande dismantled the Jungle -- a squalid camp that at its height was home to some 10,000 people -- in October 2016.
But hundreds of people continue to camp out in Calais, hoping to stow away on trucks heading to Britain, a destination seen as an El Dorado by some migrants from Afghanistan and East Africa.