Analysts described the shift out of technology names as a reallocation after the sector's banner run. The move also reflects the expectation that many growth stocks are not the biggest winners under the massive tax plan now moving through Congress.
The Dow Jones Industrial Average finished up 0.2 percent at 24,290.05, a new record.
But the tech-rich Nasdaq Composite Index slid 1.1 percent to 6,775.37, while the broad-based S&P 500 dipped 0.1 percent to 2,639.44.
Banks gained, with JPMorgan Chase rising 2.1 percent and Bank of America 3.5 percent.
Retailers also were winners, with Macy's surging 6.7 percent, Lowe's 4.5 percent and Best Buy 3.7 percent.
But technology shares languished, as Amazon lost 2.4 percent, Facebook 2.1 percent and Microsoft 3.8 percent.
Insurer Aetna shed 1.4 percent after agreeing to be acquired by drugstore chain CVS Health for $69 billion in a move that would broaden the pharmacy's traditional functions to include clinics and more nuts-and-bolts health services. CVS fell 4.6 percent. Both companies were put on watch for downgrades by S&P.
Disney shot up 4.7 percent on reports it was in talks to buy assets from 21st Century Fox and after its animated movie "Coco" led the box office last weekend.
Other media stocks also gained, including Comcast, which advanced 4.9 percent and Time Warner 1.5 percent.