Cristiano Ronaldo's return to La Liga after five-game ban was ruined by late Antonio Sanabria header as Real Betis upset Real Madrid at Santiago Bernabeu to clinch 1-0 victory.
Sanabria scored an injury time header at the 94th minute of the game to end Madrid’s 73-match goal scoring streak.
Former Real Madrid goalkeeper Antonio Adan returned to the Santiago Bernabeu to haunt his former employers.
Adan produced stunning saves from Isco, Toni Kroos and in particular Gareth Bale's stunning back-heeled effort on his right foot as Real fired a blank for the first time in 74 games.
And then, in the fourth minute of time added on, Betis broke and Sanabria was found at the back post to head home the winner.
With the defeat, the defending champions are now seven points behind the league topper Barcelona.
It could even have been worse for Madrid had Dani Carvajal's goalline clearance and Keylor Navas' brilliant save from Fabian not thwarted a bright start by Betis.