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Tsurenko, the seventh seed who advanced when top-seeded Mirjana Lucic-Baroni retired from their semi-final with illness, got off to a hot start and held on to notch her fourth win over France's Mladenovic in five career meetings.
Tsurenko has now won a title in each of the past three years -- emerging triumphant in all three of her career finals appearances.
Tsurenko rolled to a 5-0 lead and in a second set in which service breaks were the norm she earned what proved the decisive break in the 11th game and then held for the win.
Mladenovic was denied a second career title to go with the St. Petersburg trophy she lifted last month.