Skipper Misbah was the top scorer for United with 61, Sam Billings 37 and Dwayne Smith 31.
Among Qalandars Grant Elliott was the pick of the bowlers grabbing four wickets, the New Zealander claimed openers Dwayne Smith, Sam Billings and the dangerous Brad Haddin and Shane Watson in his bowling spell.
Sohail Tanvir and Sunil Narine picked up one wicket each.
TEAMS
Lahore Qalandar: Brendon McCullum (c) ,Sunil Narine, Umar Akmal, Sohail Tanvir, Jason Roy, Yasir Shah, James Franklin, Mohammad Rizwan, Cameron Delport, Azhar Ali, Aamer Yamin, Zafar Gohar, Fakhar Zaman, Bilawal Bhatti, Ghulam Mudassir, Usman Qadir.
Islamabad United: Misbah-ul-Haq (captain), Shane Watson, Samuel Badree, Mohammad Sami, Khalid Latif, Brad Haddin, Sam Billings, Hussain Talat, Amad Butt, Dwayne Smith, Zohaib Khan, Ben Duckett, Shadab Khan, Ruman Raees, Saeed Ajmal, Imran Khalid, Asif Ali, Syed Muzammil Shah, Steven Finn.