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The Hang Seng Index fell 0.18 percent, or 38.65 points, to 22,020.75 at the close. It sank more than three percent this week.
The benchmark Shanghai Composite Index climbed 0.17 percent, or 5.30 points, to 3,122.98, although it lost 3.40 percent for the week.
The Shenzhen Composite Index, which tracks stocks on China's second exchange, gained 0.95 percent, or 18.73 points, to 1,991.64 but ended the week 3.79 percent lower.