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The Hang Seng Index fell 0.44 percent, or 100.86 points, to 22,760.98.
The benchmark Shanghai Composite Index climbed 0.54 percent or 17.51 points, to 3,232.88 but the Shenzhen Composite Index, which tracks stocks on China's second exchange, slipped 0.35 percent, or 7.36 points, to 2,070.01.