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The Hang Seng Index fell 1.35 percent, or 308.02 points, to end at 22,531.09.
The benchmark Shanghai Composite Index rose 0.78 percent, or 24.76 points, to 3,196.04 and the Shenzhen Composite Index, which tracks stocks on China's second exchange, gained 0.53 percent, or 11.14 points, to 2,108.03.