Retail sales in Latin America's second-largest economy climbed 1.2 percent from the previous month in seasonally-adjusted terms, the national statistics agency said.
The increase in retail sales tracked gains in consumer confidence, which hit a record peak in February.
The consumer confidence reading had been on the rise since Lopez Obrador took office in December, though it dipped in March, according to the statistics agency.
The finance ministry this month lowered its growth estimate for the economy in 2019, to between 1.1 percent and 2.1 percent from a previous estimate of 1.5 percent to 2.5 percent. Private sector economists have also cut their forecasts.
Ratings agencies have warned in recent months that Mexico is at risk of a downgrade to its credit rating.
Compared with the same month last year, retail sales rose by 1.8 percent in February, the agency's data showed.