Malik suffered a rib injury and missed the last game on Friday, also in Dubai, and was rested once again for the final match.
Pakistan made only one change from the fourth one-day which Australia won by six runs to lead the series 4-0, bringing in fast bowler Mohammad Abbas for Mohammad Hasnain.
Australia replaced fast bowler Nathan Coulter-Nile with Jason Behrendorff.
Teams:
Pakistan: Imad Wasim (capt), Shan Masood, Abid Ali, Umar Akmal, Haris Sohail, Saad Ali, Mohammad Rizwan, Usman Shinwari, Yasir Shah, Mohammad Abbas, Junaid Khan
Australia: Aaron Finch (capt), Usman Khawaja, Shaun Marsh, Peter Handscomb, Glenn Maxwell, Marcus Stoinis, Alex Carey, Nathan Lyon, Adam Zampa, Jason Behrendorff, Kane Richardson
Umpires: Michael Gough (ENG) and Ahsan Raza (PAK)
Tv umpire: Kumar Dharmasena (SRI)
Match referee: Jeff Crowe (NZL)