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Sam Lahood, Egypt director for the International Republican Institute and the son of a US government minister, was not allowed to travel on Sunday "on the orders of the prosecutor general", the official told AFP.
The move, which comes amid a crackdown on foreign-funded NGOs, is likely to further strain relations between Egypt and the United States after prosecutors last month stormed the offices of groups including IRI as part of a probe into allegations of illegal funding from abroad.