Scientists say they have moved a step closer to developing a computer model of the brain after finding a way to map both the connections and functions of nerve cells in the brain together for the first time.
In a study in the journal Nature on April 10, researchers from Britain's University College London (UCL) described a technique developed in mice which enabled them to combine information about the function of neurons with details of their connections.
The study is part of an emerging area of neuroscience research known as 'connectomics'. A little like genomics, which maps our genetic make-up, connectomics aims to map the brain's connections, known as synapses.
By untangling and being able to map these connections - and deciphering how information flows through the brain's circuits - scientists hope to understand how thoughts and perceptions are generated in the brain and how these functions go wrong in diseases such as Alzheimer's, schizophrenia and stroke.
"We are beginning to untangle the complexity of the brain," said Tom Mrsic-Flogel, who led the study.
"Once we understand the function and connectivity of nerve cells spanning different layers of the brain, we can begin to develop a computer simulation of how this remarkable organ works."
But he said would take many years of work among scientists and huge computer processing power before that could be done.
In a report of his research, Mrsic-Flogel explained how mapping the brain's connections is no small feat: There are an estimated one hundred billion nerve cells, or neurons, in the brain, each connected to thousands of other nerve cells, he said, making an estimated 150 trillion synapses.