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Spot yuan traded at 6.1203 per dollar by midday, 0.01 percent weaker than the previous close.
The People's Bank of China (PBOC) set the midpoint at 6.1413, down 0.6 percent from Monday's fix.
The yuan has stayed on a general upward trend since May, appreciating 2.3 percent since the end of April, buoyed by China's strong foreign trade surpluses.