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The unmanned aircraft fired four missiles, hitting the compound and a vehicle parked in the Gorwaik area of Datta Khel town, 45 kilometres west of Miranshah, the main town in North Waziristan tribal district, a senior official based in Peshawar, the regional capital told AFP.
"Two missiles struck the compound and another two hit a vehicle," the official said. "At least 10 militants were killed in this American drone attack."
A second security official based in Miranshah confirmed the death toll.
Both officials said the number of casualties could rise as the area of the drone strike had been completely destroyed.
Copyright AFP (Agence France-Presse), 2011