The minister said that the patient was 86 years old and a resident of Karachi. He had a history of hypertension and had tested positive yesterday.
Meanwhile, 20 new cases of coronavirus have been reported in Sindh.
The minister said about 12 cases have emerged in Karachi, while eight have been detected among pilgrims who arrived in Sukkur on March 31. Nine patients have recovered from the disease, she maintained.
The total number of patients in the province has reached 763.
Earlier, Special Assistant to Prime Minister on Health Zafar Mirza said that 31 people have so far died of coronavirus in the country.
Addressing a media briefining, he said the number of coronavirus patients in the country has reached 2,291 figure. He said 107 patients infected with the disease have recovered.
Zafar said that nine patients suffering from the disease are in critical condition.