Nissan's chief quality officer Christian Vandenhende will oversee Infiniti's global operations effective immediately, until a new brand chief is named, Infiniti said in the statement.
Meunier was named global chief in early January after its previous boss Roland Krueger also left the Hong Kong-based brand.
In Infiniti spokesman said Meunier's resignation was not related to Nissan's internal investigation into its former leader Carlos Ghosn, adding that it was a personal decision.