Cryan said that the bank would be significantly affected, though in a way different from other banks because Deutsche Bank already has a headquarters in the EU and operates with a branch in London. For Deutsche, the Bank of England would gradually become more important as a regulator.

In the first instalment of a video series for staff called "Tower Talk: John Cryan on Brexit," Cryan sat down with Deutsche Bank's head of communications Joerg Eigendorf at the bank's London headquarters.