Pakistan, who trail the three-match series after a 93-run defeat in the first game in Sharjah on Tuesday, brought in left-arm spinner Raza Hasan for his one-day debut in place of allrounder Anwar Ali.
Australia too boosted their spin attack by replacing paceman Sean Abbott with left-arm spinner Xavier Doherty.
The third and final game will be played in Abu Dhabi on Sunday.
Teams:
Pakistan: Misbah-ul-Haq (capt), Ahmed Shahzad, Umar Akmal, Fawad Alam, Asad Shafiq, Sarfraz Ahmed, Shahid Afridi, Raza Hasan, Mohammad Irfan, Wahab Riaz, Zulfiqar Babar.
Australia: George Bailey (captain), David Warner, Aaron Finch, Steven Smith, Glenn Maxwell, Brad Haddin, James Faulkner, Kane Richardson, Mitchell Johnson, Nathan Lyon, Xavier Doherty.
Umpires: Nigel Llong (ENG) and Shozaib Raza (PAK)
TV umpire: Richard Illingworth (ENG)
Match referee: Javagal Srinath (IND)