Ankara and Washington have been at odds over issues including Syria policy, human rights and the S-400 air defence acquisition, over which the United States has sanctioned Turkey and removed it from its F-35 fighter jet programme.
"On the S-400s, we reminded them once again why Turkey had to buy them, and repeated that Turkey had bought them and this is a done deal," Cavusoglu told.
"Secretary Blinken reiterated our commitment to supporting the defense of Saudi Arabia and strongly condemned recent attacks against Saudi territory from Iranian-aligned groups in the region," the department said in a statement, adding the two also discussed human rights and social and economic reforms in Saudi.
The visit, from March 15 to 18, to Tokyo and Seoul is the first overseas trip by top cabinet members of President Joe Biden's administration and follows last week's Quad alliance summit of the leaders of the US, Japan, Australia and India.
The Quad summit pledged to work to ensure a free and open Indo-Pacific, a major priority for Tokyo, and cooperate on maritime, cyber and economic security in the face of challenges from Beijing.