The English champions move onto 92 points with three wins from their final four games enough to break Manchester City's record of 100 points from two seasons ago.
Goals from Alexander-Arnold, Mohamed Salah, Fabinho and Sadio Mane left Liverpool needing two points to secure their first English league title in 30 years.
The league returned after a 100-day hiatus due to the COVID-19 pandemic and the teams and match officials sent out a strong statement of support for the worldwide protests against racism.
The kneeling protest followed a moment's silence before kickoff