Lewandowski, who has netted 35 times in the league this season, is hoping to hit the ground running in the last four matches as he chases Gerd Mueller's all-time Bundesliga record of 40 goals in one season in 1971/72.
For Flick, however, securing their ninth consecutive league crown on Saturday is the top priority. Bayern are in top spot on 71 points, 10 ahead of second-placed RB Leipzig.
Spaniard Guardiola spent trophy-laden seasons with Barcelona and Bayern Munich before joining City ahead of the 2016-17 season and has since guided them to two league titles, three League Cups and the FA Cup.
"I had incredibly hungry teams in my career, lucky to be together in Barcelona and Bayern. To do what we've done in these four years, still winning ... these guys have something special," Guardiola told reporters.
Bayern have won six titles in the past nine months but have stumbled in their last two league matches with a 3-3 draw against visiting Arminia Bielefeld and a 2-1 defeat on Saturday by Eintracht Frankfurt.
"We know what has happened in the past days," Flick said on the two matches last week. "Against Lazio I want us to be there as a team from the start.