The comments came a day after Al-Jazeera broadcast the results of a nine-month investigation it commissioned on Arafat's 2004 death, which found the Palestinian leader could have been poisoned with the radioactive substance polonium.
Senior Palestinian official Saeb Erakat called for an investigation into Arafat's death.
"We call for the formation of an international investigation committee, modelled on the international investigation committee set up to look into the assassination of former Lebanese prime minister Rafiq Hariri," he told AFP.
And Tawfiq Tirawi, who led a Palestinian probe into Arafat's death, said Palestinian authorities would be willing to allow an analysis of samples from the leader's remains -- which are buried in Ramallah -- if his family agrees.
"After the Al-Jazeera broadcast I met today with president (Mahmud) Abbas and recommended accepting an analysis of the body of the martyr president Arafat, and Abbas for his part agreed on the condition that the family ... accepts," he said.
The Al-Jazeera investigation centred on forensic testing of items belonging to Arafat, including clothing worn by him, which were handed to his widow Suha by the Paris hospital where the Palestinian leader died in 2004.
Suha Arafat gave Al-Jazeera permission to take the items, which contained strands of Arafat's hair and traces of sweat, urine and blood, for testing at several European laboratories, including in Switzerland.
Francois Bochud, head of the Institute of Radiation Physics at the University of Lausanne, who cooperated with Al-Jazeera on the investigation, said the testing revealed high levels of polonium.
"The conclusion was that we did find some significant polonium that was present in these samples," he told Al-Jazeera.
But to confirm the theory that the Palestinian leader was poisoned by polonium it would be necessary to exhume and analyse Arafat's remains, Bochud said.
"If (Suha Arafat) really wants to know what happened to her husband (we need) to find a sample -- I mean, an exhumation... should provide us with a sample that should have a very high quantity of polonium if he was poisoned," he said.
Polonium was used to kill Russian former spy turned Kremlin critic Alexander Litvinenko, who died in 2006 after drinking tea laced with the substance at a London restaurant.
Tirawi said the Palestinians would be willing to cooperate with Bochud's lab.
"We are in agreement that if the family of the martyr Yasser Arafat agrees, we will contact the Swiss lab in the coming days so that they can come and collect the samples they need," he told AFP.
Abbas's spokesman Nabil Abu Rudeina told AFP the Palestinian Authority "is ready to cooperate fully and provide all necessary facilities to uncover the real reasons behind the illness and death of the former president."
"There is no religious or political reason that would prevent a reexamination of this question, including an examination of his remains, with the approval of his family."
Suha Arafat, in an interview with AFP on Wednesday, said she would push for her husband's body to be exhumed so further tests could be carried out.
"I will immediately address an official letter to the Swiss laboratory that conducted the tests ... to authorise the collection of samples from the remains of the martyr Arafat to verify the results and accelerate the uncovering of the truth about the assassination of Arafat," she said.