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The Hang Seng Index fell 239.11 points to 22,900.94 on turnover of HK$68.60 billion ($8.85 billion).
In mainland China the benchmark Shanghai Composite Index fell 0.72 percent, or 17.17 points, to 2,356.50 on turnover of 203.8 billion yuan ($33.3 billion).
The Shenzhen Composite Index, which tracks stocks on China's second exchange, lost 1.35 percent, or 18.23 points, to 1,332.90 on turnover of 207.7 billion yuan.