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The plane came down inside the airfield boundaries and rescue crews rushed to the scene, said a NATO spokeswoman at Bagram, a key transport hub for US-led military operations in Afghanistan.
The spokeswomen told AFP that no information was available on how many people were on board the flight from Bagram, 50 kilometres (30 miles) north of Kabul, or on any casualty figures.
Aircraft crashes are fairly frequent in Afghanistan, where the 100,000-strong international military mission relies heavily on air transport as it battles insurgency across the country.
A NATO plane crashed in the south on Saturday, killing four service members, in another incident that the coalition said was not due to insurgent fire.